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Although, these melanocytic capsular nevi appear benign morphologically, a low probability that they may represent subtle metastases was also considered.
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Adiponectin bioavailability for target cells under metabolically challenging conditions is reduced due to reduced trans-endothelial transport and may represent a subtle target for improving insulin sensitivity.
It has also been suggested that a missed or shortened treatment may represent a subtle expression of control over their health status [ 12].
Moreover, differences by site despite consistency in training and protocol management may have represented subtle differences in personnel and in implementation of the protocol.
These represent subtle, yet observable, small-scale shifts in how social roles were redefined and materialized.
Instead, they represent subtle, yet systematic, structural differences between the fibrils in the sample.
The observed association between maternal stress during pregnancy and child health may represent long-term consequences of subtle adaptations in multiple organ systems to the intrauterine environment (Bateson et al. 2004).
These subtle abnormalities of pulmonary function may represent subclinical lung injury, which are undetectable by standard techniques and current clinical definitions.
The clinical importance of these subtle findings is unclear, but they may represent signs of early diastolic dysfunction.
This subtle shift in mode of inhibition may represent a useful direction for further development, because mixed inhibitors are less susceptible to the effects of substrate accumulation than competitive inhibitors.
113– 115 Taken together, these findings suggest that various biological parameters may serve as subtle but significant markers of treatment response to MBIs, and they may represent mechanisms through which psychosocial function could impact physical health.
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