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In some cases, these unexpected signals may represent stochastic noise, spurious associations that do not reflect any underlying genetic heritability.
While this may represent stochastic variation among libraries, our preliminary studies of various libraries showed little variation in relative genomic representation between independently generated and sequenced libraries (data not shown).
Methylation of pattern 1 DMRs is inversely correlated with pathological grade and may represent stochastic demethylation of heterochromatic DNA through a loss of a maintenance-like process, or may be a product of the formation of partially methylated domains (PMDs) [ 45] in a subset of tumors.
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This mapping transforms a high-dimensional random parameter vector, which may represent the stochastic input load as well as any uncertain structural parameters, into a random variable with unknown distribution, which represents the uncertain structural response.
Third, the release of asexual propagula containing several mature larvae [ 31] may represent a stochastic dispersal event.
However, a significant subset of DMRs is shared among iPSC lines of different genetic background and cell type of origin, and is transmitted through differentiation, suggesting that at least some DMRs may represent non-stochastic epigenomic hotspots that are refractive to reprogramming.
Models that include stochastic reactions can represent stochastic processes in cells, such as stochastic gene expression [ 76] or a probability of tumor formation.
In this graph, nodes represent the random variables and directed edges represent stochastic dependencies among variables.
Thus, fluctuations in the annual incidence rates, for example, from 1987 to 1988, could well represent stochastic variation.
In addition, exportations represent stochastic events, with chance determining the actual path.
Uniform and F_prop models represent stochastic algorithms whilethe min F model is deterministic.
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