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Chemotherapy-induced neutropenia and oral mucositis may represent predisposing factors.
Oro-intestinal colonisation by Granulicatella spp. and subsequent mucositis may represent predisposing factors for bacteraemia in neutropenic patients, as it is well documented for viridans streptococci [ 41, 42].
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Marital status, age, sex and time since immigration represent predisposing characteristics.
In other words, people with unhealthy sleeping habits earlier on in life may be predisposing themselves to these diseases.
The effects of the Gram-negative bacterial wall components lipopolysaccharide (LPS) and bacterial lipoprotein (BLP) on VEGF receptor function and expression are unknown and may represent an important biological mechanism predisposing to delayed wound healing in the presence of localized or systemic sepsis.
This viral activity may represent the baseline upon which addition viral activities that predispose to malignant change can be appended.
We propose from these data that the 17q11.2-q12 region contains a novel predisposing gene in Barrett's adenocarcinomas and may represent the site of a tumour-suppressor gene.
37 Similarly, ineffective clearance of defective mitochondria by impaired mitophagy predisposes cells to apoptosis, 38 and this may represent another explanation for our findings.
Further support for this hypothesis is that not all humans develop DDD as opposed to aging, suggesting an underlying genetic switch or series of switches that may predispose some people to DDD [ 31, 32] The CD canine may represent a similar genetically predetermined subset of animals that, like humans, is notochordal cell deficient and susceptible to degenerative change [ 12].
Potentially, such SNPs may represent sites at which risk alleles have major impacts on TF/uDBP-PRE interaction, with important downstream consequences that predispose to psoriasis, or genetically-related autoimmune diseases [96].
And they may represent a relative bargain.
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