Whatever the mechanisms, it seems likely that the abnormal processing of cortical information may represent a necessary link between stress, psychological factors and development of migraine attacks.
Although the neighbouring genes of mazF do not show any sequence similarity to mazE, one of them may represent the necessary antitoxin.
Because IL-10 usually exhibits human macrophage deactivating properties, high levels of IL-10 may represent a necessary counterbalance to an extremely polarized immune response thereby limiting the tissue damage[52].
Thus, PINK1 phosphorylation of substrates may represent a necessary early event that triggers the subsequent action of parkin and of the proteasome.
Conversely, in the progression of breast and prostate carcinomas, dyskerin overexpression may represent a secondary change necessary to meet the requirements for increased RNA biosynthesis and telomerase activity.
Therefore, it might not be necessary to separate the reads in these components, since these components may represent regions with the significant biological functions necessary for both species.
The construct MUC1*1110, truncated after only forty-five (45) amino acids of the extracellular domain, may represent the minimal region of MUC1 necessary for its oncogenic function.
Its regulation in this experimental system may represent part of the nutritional adaptation necessary to acquire inorganic phosphorous from the growth medium after emergence from iDC rather than indicating a strict starvation response since the growth medium was nutrient replete.
An alternative explanation is that higher grey matter values may represent increased neural resources that are a necessary precursor to learning, facilitating the acquisition of a given skill.
They may represent a disrupting feature of sleep but may also be necessary for normal, healthy sleep and are associated with autonomic activation [84].
