Apart from the ethical considerations, which are important and discussed below, this may represent serious issues with hydration.
Therefore, the clinical trial design and data collection procedures are unclear and may represent critical issues for evaluation of the SNP data.
All above mentioned processes may represent safety issues, be time-consuming for patients, their relatives, or carers in charge of the medication managements, and ultimately generate costs that may clear the savings initially advocated for splitting tablets [ 30].
Although Jonsen et al lament that the ethical issues here may be less evident, they in fact may represent the same issues discussed above.
This highlighted human orthologs that map to more than one GLEAN5 model, which may represent local assembly issues in the bovine genome assembly and/or incomplete gene models.
This selective control of the cell-surface interaction by topography may represent a key issue for the future stent material design.
A SVM is employed to implement the prediction system; such choice is possibly motivated by the need to exploit a ML paradigm that is less prone to the curse of dimensionality, which may represent a major issue when dealing with a 256-dimensional input space.
Nevertheless, the results may represent an important issue in the clinical practice and should be taken into account in designing future clinical trials based on anti-EGFR therapies.
Toxicity monitoring may constitute a substantial proportion of the cost associated with preventive therapy, and economic, human, and financial sustainability may represent a key issue in limiting a wide implementation of programmatic LTBI management.
This lack of association between brevetoxin exposure and PFT results may represent insensitivity or timing issues of the pulmonary function measurements and/or exposure to brevetoxins near the threshold of toxicity, both of which will be explored in the future.
