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Alternatively, they may represent editing intermediates.
Even though partial editing may represent editing in progress in intermediate reaction products [ 53] the discrepancy in silent and non-silent sites is more consistent with a functional explanation.
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Since in mouse this position has not been mapped as a genomic single nucleotide polymorphism (SNP) and the sequence alteration is within the highly conserved R-domain sequence motif, this base discrepancy may represent a site of RNA editing.
Although it does not happen often, undisclosed paid advocacy editing may represent a serious conflict of interest and could compromise the quality of content on Wikipedia".
This activity may represent a relic of editing exhibited by a primordial aaRS consisting solely of the catalytic module.
VANTED [ 44] loads and edits graphs, which may represent biological pathways or functional hierarchies.
The presence of edited sites may represent a "burden", since they are dependent on specific recognition sequences and trans-factors that need to be conserved to maintain editing activity.
SlideSort provides an undirected graph G, where vertices represent short reads and weighted edges represent edit distances of neighbor pairs.
These may represent sequencing errors (when occurring in low copy numbers), mutations and/or RNA editing events.
These mismatches are common in arthropod mtDNAs and can be corrected through editing processes (e.g., [ 73]) or may represent unusual pairings [ 74].
To address these issues, high-throughput sequencing studies that are designed to monitor ribosome occupancy on protein-coding transcripts [ 59] may represent an ideal approach for characterizing the effect of ADARs and RNA editing.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com