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Inducible NOS-mediated intracellular killing may represent direct bactericidal activity, because B. mallei showed an exquisite sensitivity to NO generated chemically.

This induction may represent direct transcriptional regulation by PPARγ, as the proximal Gcm1 promoter contains at least one putative "atypical" PPARγ-response element (PPRE) [23], [24, and data not shown].

Such long-term consequences of maternal vaccination may represent direct, permanent effects of maternal antibody transfer on offspring immunology (Lemke & Lange 1999; Grindstaff et al. 2006).

Thus in zebrafish, a small subset of genes is highly sensitive to Spt5 levels during embryogenesis, suggesting that they may represent direct targets of regulation by Spt5.

More broadly, we observed similar shifts in gene expression between the miR-1-1 and miR-1-2 knockout mice (see number 2 below, Figure 2 figure supplement 2), some of which may represent direct targets.

Two thousand four hundred and fifty-four SNPs were found, 7% of which were identified as outliers that may represent direct targets of selection or regions tightly linked to selected loci.

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While some of the transcripts altered may not represent direct targets of the corresponding miRNA, further analysis of individual candidate mRNAs can provide evidence as to whether they represent direct or secondary targets.

We put the most concern in c1, c2, and c9, c10 which may represent the direct response to the continuous decrease of DO and all genes inside c1, c2 were down-regulated, and all genes within c9, c10 were up-regulated during the whole fermentation process (Fig. 3b).

These may represent the direct and indirect transcriptional effects of the PRC coactivator.

Reduced ribosome activity may represent a direct response to stress-repressed overall protein translation.

This suggests that neglected swimming pools may promote WNV amplification, and may represent a direct link between declining economic conditions and a favorable environment for WNV propagation.

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