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Thus, CSCs may represent differentiated descendants of COCs.
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Most likely, CD4+CD25− T-cells may represent terminally differentiated CD4+ T-cells [9].
After 3 days of culture, virus-specific antibody secreting cells in splenocyte cultures surpassed those in bone marrow (Fig. 7B), which may represent rapidly differentiated virus-specific memory B cells.
The majority of the detectable Tregs in islets are phenotypically CD4+Foxp3+Bcl-2loKi67+, which may represent newly differentiated iTregs at the site of inflammation.
On the basis of their morphology and ability to induce SOX9 and/or COL2A1 expression, we hypothesize that our different immortalized subtypes may represent more differentiated (NP-nR, cobblestone) or more progenitor-like (NP-R, wavelike) cell types.
Finally, a small number of colonies were composed only of T(Bra) -Sox2 - negative cells which may represent more differentiated NMP derivatives such as spinal cord cells or mesodermal lineages other than paraxial (e.g. lateral/ventral) derived from sorted TGFP +Sox2 - cells.
The accumulation of C6 cells in the G1 phase may represent a differentiation process leading to differentiated astrocytes.
It is now known that each of these processes occur in both compartments of GC lymphocytes and that the GC T-cell represents an unusual Thy-1 subset of alpha beta T-helper cells that may represent a terminally differentiated cell that is lost with the end of the GC reaction.
The observed PAX3-negative, MLANA-positive epidermal melanocytes may represent mature terminally differentiated melanocytes.
Previous data suggests that normal ER+ cells may represent either relatively differentiated luminal cells with limited progenitor capacity or primitive progenitors with stem cell properties in the luminal cell compartment [4], [24], [25].
Therefore, it seems that FPR+ malignant glioma cells may represent a more poorly differentiated cell population with higher degree of malignancy.
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