It is also possible that some alterations of gene expression may represent disruption of calcium sensitive pathways as a result of the transfer shock which we cannot distinguish at present from those of acclimation.
Using the vast body of knowledge accumulated on calcium granulations, the same author questions whether similar bodies seen in human tissues, like Randall's plaques, are really the precursors of pathologies or perhaps, as she infers, they may represent innocuous or byproduct calcium deposits that are part of a more general calcium homeostatic and clearance cycle.
Intracellular calcium homeostasis is among the functions of ER and aberrant calcium distribution may represent a typical manifestation of ER stress.
These calcium granulations are similar to those found in organisms throughout nature and may represent the products of more general calcium regulation pathways involved in the control of calcium storage, retrieval, tissue deposition, and disposal.
Increased mitochondrial calcium uptake may represent a 'weak point' in cellular compensation as this over time may contribute to cell death.
Increased mitochondrial calcium uptake may represent a 'weak point' in cellular compensation as this over time may contribute to cell death (Ichas & Mazat, 1998; Thibault et al., 1998; Begley et al., 1999).
This acute treatment may represent an additional contribution of cytosolic calcium to PrPRES neurotocxicity due to mitochondrial calcium overload as suggested in models where cells were treated with micro molar concentrations of PrP peptides [40].
The recognition of the IC3 loop from the dopamine D2 receptor by apo-S100B may represent a new type of calcium-insensitive target interaction for an S100 protein.
CIB4, encoding calcium and integrin binding family member 4, may represent a further HGF candidate gene considering that calcium channel blockers can induce gingival hyperplasia.
This protein binding to calcium and apatite may represent a general mechanism of protection deployed within the blood compartment and possibly within all the other body fluids that serves to cope with calcium and/or phosphate loading.
