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Exact(4)
However, it is worth noting that some portion may represent bona fide products of the spliceosome machinery [Additional file 8].
From the results of the expression analysis it could be inferred that the ETS revealing expression in the bovine multi-tissue panel may represent bona fide transcribed sequences.
In addition, established cancer genes like Lmo2, RhoH, Trim33, Mll, and Hspca (Futreal et al., 2004) are candidate target genes of less frequently mutated CISs, indicating that lower ranked CISs (carrying 4 5 insertions) may represent bona fide cancer genes.
While this suggests that it is indeed likely that the P-element promoter and translational start sites facilitate enhancer trapping, some of the traps may be located in introns associated with unannotated 5' exons and thus may represent bona fide protein traps.
Similar(56)
For applications requiring a comprehensive transcriptome profile, coverage exceeding 10 million fragments per sample may be needed, with the understanding that increasing depth can lead to detection of sequences that may not represent bona fide transcripts.
As with any genomic study, these targets likely include false positives, but four findings suggest that they may largely represent bona fide targets.
Our microarray analysis indicated that 19 CesA probe sets were categorized in cluster 10 (Fig. 4b red colored probe sets), and may therefore represent bona fide secondary cell wall specific cellulose synthase genes.
Their absence in Fugu may represent a bona fide gene loss.
These results suggest that up-regulation of TERT under ER stress may represent a bona fide cellular process involved in the ER stress response.
Due to the short lengths of contigs and scaffolds, presumably caused by insufficient coverage of the comparatively large genome, the model may include predictions that do not represent bona fide protein-coding genes.
More generally, all kinds of chimeric transcripts could be the product of the normal cell transcriptional process, not discarding the possibility that they may constitute the "noise" of this process, and thus represent bona fide biological artefacts, with or without function.
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