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We propose here that these tumours may represent biologically important disease entities of breast cancers.
Furthermore, we also report genes with at least two-fold change, which may represent biologically meaningful differential expression levels.
This resulted in noisier clusters, but some of the "noise" may represent biologically relevant information, as we found here.
Breast tumors have estrogen or progesterone receptors, and tumor subtypes defined by these receptors may represent biologically different entities [ 23, 24] and influence the survival of patients.
Components of these two pathways are frequently abnormal in a variety of cancer tumors and may represent biologically relevant targets for anti-cancer therapy [ 57- 59].
Thus, PCs with small contributions may represent biologically critical differences between samples, as shown in Figure 2, where the contributions of samples to PC2s are demonstrated.
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The statistical significance of these measures suggests a deviation from no fixation, however the low estimates of FST may not represent biologically meaningful levels of structure.
Although remote sensing maps are superior in the fine detail they provide at regional and local level across the continent, such 'structural maps' do not consider floristic similarity and hence may not represent biologically meaningful units.
Finally, the haplotype may represent the biologically functional genetic unit rather than the genotypes [4].
Second, mixed tissue viral branches that occur between the non-tumor and tumor clades may represent a biologically ancestral form of the tumor virus.
Our findings may represent promising biologically relevant markers for lung cancer prognosis or therapeutic intervention.
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