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We have recently discovered several novel classes of quinazolinones, quinazolidinones, and quinoxalines as potent PARP-1 inhibitors, which may represent attractive therapeutic candidates.
On the other hand, other seemingly less attractive areas, such as deep horizons in deep-water basins, may represent attractive targets for new exploration as a result of the interaction of technological advancement, and financial and market factors.
Therefore, deregulated protein kinases may represent attractive targets for the development of therapeutics against various human disorders.
These observations suggest that EBNA1 is a member of a family of viral origin binding proteins that have no apparent orthologue in the human genome, and therefore may represent attractive targets for inhibitors of viral latent replication and persistence.
Therapies aimed at redressing this imbalance may represent attractive anti-fibrotic strategies.
Thus, the immunophilin co-chaperones perform important functions in a number of cancers, and may represent attractive therapeutic targets in some malignancies.
Similar(49)
The identified pathways and genes, particularly Chmp7, may therefore represent attractive molecular targets for development of a therapeutic approach for SBMA.
Being orchestrators of leukocyte trafficking, many chemokines are involved in directing leukocytes to sites of vascular inflammation and may thus represent attractive targets for drug therapy.
The heterologous epitope-peptide from different viruses may represent an attractive candidate vaccine.
The biologically optimized GDF5 mutant BB-1 may represent an attractive drug candidate for this purpose.
Treating the underlying allergy may represent an attractive method of asthma prevention.
More suggestions(15)
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may represent longer-term
may represent unburnt
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CEO of Professional Science Editing for Scientists @ prosciediting.com