Sentence examples for may represent accumulation from inspiring English sources

The spontaneously elevated nuclear Rad51 foci observed in BS cells [47] and Recql−/− cells [8] may represent accumulation of unresolved recombination intermediates or a greater load of endogenous DNA damage in the absence of the RecQ helicase.

This interesting discrepancy between mRNA levels and detectable immunoreactivity may reflect differences in the stability of Kiss1 mRNA and kisspeptin protein, or may represent accumulation of kisspeptin intracellularly due to the absence of a stimulus for release.

This would explain the occurrence of discreet foci of fluorescence, which may represent accumulation of mis-folded Cys326-OGG1 under conditions of oxidative stress and would also explain the reduced repair capacity of Cys326-OGG1 specifically under conditions of oxidative stress observed previously [27].

PIN gene expression may represent auxin accumulation (Xu et al., 2006; Huang et al., 2010).

It may represent an accumulation of misfolded, damaged or unwanted proteins, awaiting or undergoing degradation.

Because PINK1 controls autophagy in other systems, increased fragmentation due to pink-1 (RNAi) in C. elegans may represent an accumulation of fragmented mitochondria due to alterations in autophagic capabilities.

It may represent an accumulation of misfolded, damaged or unwanted proteins, waiting for degradation via proteolytic mechanisms, though the precise pathway that this might enter, or fail to enter, for such a purpose remains unclear.

This may represent the accumulation of the genetic background (e.g. HLA class II susceptibility alleles (DRB1*1501), IL2R or IL7R for MS) [ 48], in conjunction with the shaping of the immune repertoire during ontogeny and the presence of stochastic infectious challenges for generating individuals susceptible to develop autoimmune diseases.

Alternatively, these aggregates may represent extra-accumulation of pericentriolar material without centriole replication.

However, there are number of problems associated with these responses, for example a change from satisfied to dissatisfied may represent either an accumulation of small shifts in separate component areas or large shifts in a single component [ 67].

We speculate that decreased intramuscular lipid accumulation may represent a transient compensatory mechanism to counteract insulin resistance.