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In this context, epigenetic modifications may represent accessible molecular markers of early-life events that may be more stable than direct measures of gene expression.
Whilst these experiments only represent an initial attempt to measure GRP75/Mortalin and Calreticulin levels in human patient muscle biopsies, and are limited by the very small sample size, our preliminary investigations suggest that both Calreticulin and GRP75/Mortalin may represent accessible protein biomarkers in skeletal muscle conserved between mouse models and human patients.
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In addition, surface-wipe sampling is proposed because this kind of sampling may best represent accessible surface lead to which people may most readily be exposed (Bai et al. 2003).
This work demonstrates that cryopreserved bone grafts may represent a novel, accessible source of cells for tissue regeneration therapy, and the results of our study may also stimulate the development of other cryopreservation techniques in basic and clinical studies.
While vitamin D supplementation may represent an effective, accessible and safe intervention for the prevention of URTI, many questions which might guide clinical practice remain unanswered.
Furthermore, as the visual effects that are seen in the skin following the menopause may physiologically mirror the internal effects in other tissues (bone, cardiovascular system, cancer), skin may represent an easily accessible model.
The oligomers have attenuated client binding capability and may convert to the more active monomer (Freiden et al., 1992; Blond-Elguindi et al., 1993; Chevalier et al., 1998; Thompson et al., 2012; Aprile et al., 2013), suggesting that they may represent a rapidly accessible, inactive buffer form of chaperone.
Although Y bremsstrahlung imaging is better with SPECT/CT than planar imaging, planar imaging approaches may represent a more accessible and less expensive qualitative imaging modality capable of performing faster whole-body assessment of Y radioactivity than existing SPECT/CT technology.
Field-assessed lakes generally are easily accessible and may represent a spatially irregular, non-random sample of a region.
SGL may represent one of the most accessible methods for converting a classroom from a teacher-centered setting to an active, learner-centered environment.
Internet-based VR may represent a novel, easily delivered, high accessible treatment option to support the management of dizziness in older adults in primary care.
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