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There are a number of reasons why reported Marketing Firm data may report variation.
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Due to the fact that we exclusively contact each respondent at one occasion, there is a risk that respondents may report the variation they are experiencing at a given year instead of reporting a problem of a recurring nature.
The authors report variations in the adamantane-binding pocket which may explain the broad range of responses to inhibitors reported for diverse HCV genotypes (OuYang et al., 2013).
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We investigated whether the formulation of IA HA, or its combined use with IA corticosteroid (CS), may be contributing to some of the reported variation in clinical outcomes.
The other variations identified in this study are known polymorphisms except for two unknown never reported variations which is not clear whether they may activate the tyrosine kinase in the same way as well-characterized EGFR activating mutations.
For example, an entity recognition script that identifies a newly described variation may simultaneously flag the paper in which the variation is reported for variation phenotype curation.
Moreover, several recent studies report that such variation may by due to active regulation of classical reference genes under certain experimental conditions (see: http://normalisation.gene-quantification.info).info
The use of these different systems in various reports may contribute to variations in the response rates observed, in addition to the variations caused by different distributions of known and unknown prognostic variables and possible differences in activity between the treatment regimens under evaluation.
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