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Thus, it remains to be determined whether the benefit observed after 1 or 2 years of early treatment may remain clinically relevant after 1 or 2 decades.
Although congenital cephaloceles are present at birth, they may remain clinically occult until adulthood.
30 35 H. pylori gastritis may remain clinically unapparent or evolve into severe complications.
Infection by BLV may remain clinically silent at the aleukemic (AL) stage.
These tumours may remain clinically silent until a significant liver tumour burden is present.
These implants from the tubal fimbria may remain clinically occult within the inclusion cysts and invaginations before detection 18, 19.
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Though these anomalies may often remain clinically silent, a number of women develop symptoms such as delayed onset of menstruation, hematocolpos, and dyspareunia [1], [2].
The mechanisms by which metastatic disease may be present but remain clinically undetected for such prolonged periods, presumably influenced by interactions between the melanoma phenotype and the patient's immune system, have not received sufficient attention to date [ 59].
Although cement leakage is reported as high as 73%% for both PVP types, most leakages remain clinically asymptomatic, and even small quantities of leakage may have a significant clinical impact [ 12].
The majority of Meckel's diverticulum cases remain clinically silent during the entire lifetime, and their presence may be discovered incidentally during surgery, autopsy, or when performing upper gastrointestinal studies [2, 5].
A proper diagnosis and the correct therapeutic approach therefore remain clinically challenging.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com