Sentence examples for may regulate skeletal from inspiring English sources

Importantly, it was reported that inhibition of Ang II signaling resulted in near complete attenuation of skeletal muscle hypertrophy in a model of synergist ablation [23], [24], suggesting that Ang II may regulate skeletal muscle hypertrophy.

While the role of p300/CBP in histone acetylation and transcriptional regulation is reasonably well characterized (62), relatively little is known about if and how p300/CBP may regulate skeletal muscle metabolism via nonhistone acetylation of protein targets.

The signaling of hedgehog but not of FGF, bone morphogenetic protein, or transforming growth factor- β altered in primary chondrocytes from Chsy1-deficient mice [ 81], which suggests that CS-PGs and hedgehog protein may coordinately regulate skeletal development and digit patterning.

However, the canonical Wnt pathway is downregulated in the absence of myostatin through beta-catenin, whereas the Wnt/calcium pathway is upregulated [ 57], suggesting that TRRAP may negatively regulate skeletal muscle development between the canonical Wnt and the Wnt/calcium pathways through beta-catenin at 120 d.

Both isoforms can regulate skeletal muscle growth and strength.

Subsequent studies of LRP5 and sclerostin have provided important insights into the mechanisms by which these proteins regulate skeletal homeostasis.

Thus eIF3f plays a major role for proper activity of mTORC1 to regulate skeletal muscle size.

STAT5B encodes a transcription factor that can regulate skeletal muscle growth and fiber composition.

18 Like MAT, both WAT and BAT have the ability to regulate skeletal metabolism.

Nonetheless, it is unknown whether Nur77 can directly regulate skeletal homeostasis or bone cell differentiation.

Hoxa2, a member of the Hox homeodomain family of transcription factors that regulate skeletal patterning, is found to control Runx2 expression and is required in skeletal morphogenesis [ 29].