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This challenge is compounded because a given gene may regulate several molecular events in different cell types during different developmental stages.
It is noteworthy that, beyond control of cell cycle, p27 may regulate several other functions both in myoblasts and in other cell types, such as cadherin-mediated cell-cell adhesion [4], tumor progression, apoptosis and cytoskeletal dynamics [38].
MiR-19b may regulate several genes involved in the metastasis process.
Based on GO analysis, acetylation may regulate several other cellular processes as well.
The inhibition by MICL of MSU-induced early signaling events is consistent with the known mode of action of inhibitory receptors and is strongly suggestive that MICL may regulate several MSU-induced neutrophil effector functions driven by downstream signaling events.
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In addition to controlling RAF kinases, MAPK may also directly regulate several other signaling pathway, such as the phosphatidylinositol 3 (PI3) kinase [ 13].
It is known that PTH during fetal life may act to regulate several functions of development such as epithelial cell growth and differentiation, normal bone development and mineralization, placental calcium transport, uterine smooth muscle tone, and fetal placental vessel tone (Wlodek et al. 2004).
Although initial rodent studies have produced discrepancies as to whether pro-inflammatory cytokines may regulate resistin, several recent human studies have supported the concept of inflammatory cytokine mediation of resistin [ 17, 18].
Finally, we found 414 miRNAs that may regulate one or several modules associated with clinical improvement.
RA may regulate neurogenesis via several mechanisms.
PTH signaling may regulate ATF4 via several mechanisms.
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