Sentence examples for may regulate neurogenesis from inspiring English sources

RA may regulate neurogenesis via several mechanisms.

Among the growth factors that may regulate neurogenesis, IGF-I is of particular interest given its expression pattern throughout life.

Astrocytes and other glial cells, which play an important role as sensors of changes in their extracellular microenvironment, may regulate neurogenesis by secreting local signals such as growth factors and cytokines involved in neurogenesis (Spranger et al., 1990; Yoshida et al., 1992; Kamiguchi et al., 1996; Junier, 2000; Laming et al., 2000; Scemes, 2000).

We also identified multiple transcripts that may regulate neurogenesis or encode proteins known as highly specific for neural tissue, in agreement with a few studies reporting maternal deposition of transcripts later expressed in the CNS (e.g. Drosophila, zebrafish and axolotl [ 74– 74]).

Recent results have shown that IGF-1 may even regulate neurogenesis in the adult rat hippocampus [ 56].

The effects that we observed occurred shortly after NPC expansion suggesting that Cx36 may regulate early neurogenesis during development, perhaps to fine tune the establishment of neural networks within the brain.

These findings imply that PROSPERO, in addition to its known role as cell fate determinant in GMCs, provides a transient signal to ensure a precise timing for cell cycle exit of prospective neurons, and hence may link the mechanisms that regulate neurogenesis and those that control cell cycle progression in postembryonic brain development.

This may be due to the fact that the program of post-traumatic neurogenesis in sea cucumbers is not known and, obviously, may not entirely consist of the mechanisms that regulate neurogenesis in vertebrates, whose genes were used as the reference.

Since high levels of RA (1 μM) can induce neurogenesis in P19 cells and both Pax3 and Shh signalling via Gli2 can regulate neurogenesis in spinal cord and brain [ 68- 70], the increase in Pax3 mRNA may not reflect skeletal myogenesis but, rather, result from an increase in neurogenesis.

A better understanding of the mechanisms that regulate neurogenesis is necessary to develop new therapeutic tools to cure or prevent the development of memory disorders that may appear during the course of aging in some individuals.

Moreover, RA has been shown to regulate neurogenesis in vitro by activating neurogenesis-related gene expression, including neurotrophin receptors [30].