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Export of vitamins may regulate intracellular enzyme activities by keeping substrate levels within an optimal range.
Both ORFs encode for a putative 2,5-didehydrogluconate reductase which participates in the production of ascorbate and thus may regulate intracellular redox conditions.
Specifically, it indicates that the induction of host cell death is reduced despite the fact that the cells are infected with 100 MOI F. tularensis subsp. novicida, and suggests that Akt may regulate intracellular bacterial burden.
Taken together with the finding that KRIT1 plays a role in the control of ROS steady-state levels, these results suggest that KRIT1 may regulate intracellular ROS by modulating the level of the antioxidant enzyme SOD2.
Both system A and L solute carriers may regulate intracellular amino acid bioavailability within skeletal muscle [ 47].
According to the analyses above, pLG72 may regulate intracellular response through transducing several phosphorylation and secondary messenger signaling.
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Thus, Tah18 may negatively regulate intracellular H2O2 detoxification, and/or positively promote cell death.
Considering that Dyn2 regulates intracellular trafficking [31], [32] and endocytosis of the AMPA receptor subunit GluR1 [46], [46], we propose that Ndel1 may regulate GluR1 intracellular distribution in a similar way to Dyn2.
As these PSEN-dependent surface alterations go along with a decrease in focal adhesion sites and caveolae, intracellular accumulation of cholesterol, caveolin-1 and the integrin-interacting CD47 protein [ 147, 166], we hypothesize that PSENs may regulate selective intracellular trafficking routes.
These results suggest that Ndel1 may regulate GluR1 intracellular distribution through Dyn2 GTPase activity.
Phosphorylation of residues in the vicinity of the NES and NLS may regulate the intracellular distribution of a protein [ 6].
More suggestions(15)
may inhibit intracellular
may represent intracellular
may alter intracellular
may regulate attentional
may influence intracellular
may permit intracellular
may suppress intracellular
may regulate osteoblast
may have intracellular
may regulate cortical
may regulate nuclear
may regulate cardiac
may trigger intracellular
may initiate intracellular
may regulate p27Kip1
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