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Taken together, these results demonstrate a radial glial signaling mechanism that may regulate cortical neuronal production.
These include pulvinar, which may regulate cortical 'set' for interpreting painful stimuli (Shipp, 2003); and the posterior portion of the ventral medial thalamic nucleus, which is likely to serve as a dedicated spinothalamocortical relay for pain and temperature sensations and may play a fundamental role in signalling physiological body states (Blomqvist et al., 2000).
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We argue that synchronization of neuronal oscillations may regulate cross-cortical communication, coordinating anatomically distributed neuronal activity that underpins speech comprehension (Fries 2009).
It has also been shown to regulate cortical size; enlarged cortices with increased cortical folds were observed in Ctnnb1 transgenic mice [ 80].
GSK-3 is an essential mediator of several signaling pathways that regulate cortical development.
The basal ganglia are one system likely to regulate cortical damping and resonance [ 14].
Moreover, Lis1 and Nde1 regulate cortical neurogenesis in a dosage-dependent manner.
It is presumed to regulate cortical cell membrane protrusions (Kureishy et al, 2002).
On the one side, direct cortico-cortical projections regulate cortical dynamics by transmitting fine-grained information that defines the step-by-step time course of the response of the target cortical modules.
HAPLN1 was reported to trigger the formation of perineuronal nets (35), which are extracellular matrix structures that surround many neurons, may regulate experience-dependent cortical plasticity, and increase in number during postnatal development (36).
These findings suggest that spectrin-regulated cortical actomyosin activity may regulate Hippo signaling through a different mechanism.
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