Sentence examples for may regulate cardiac from inspiring English sources

Shapiro et al. [76] conclude that the prefrontal regions may regulate cardiac changes.

Interestingly, in a study that analyzed microRNAs in human aortic valve stenosis, miR-499 levels were decreased [40], and it is possible that this decrement may regulate cardiac gene expression changes that are important in the physiologic response to cardiac pressure load.

We have shown previously that PKD1 may regulate cardiac myofilament function and the Ca2+ sensitivity of contraction by phosphorylating cTnI (inhibitory subunit of cardiac troponin) at Ser/Ser [ 7, 8] and cMyBP-C (cardiac myosin-binding protein C) at Ser [ 9].

Homozygous deletion of MIR-1 gene (MIR-1-2) in mice resulted in late embryonic lethality and sudden cardiac death among survivors, the majority of which were due to arrhythmias, indicating that miR-1 may regulate cardiac arrhythmogenicity by targeting the gap junction protein, connexin (GJA1), and potassium ion channel (KCNJ2) [ 45, 46].

We therefore postulated that rare variants in genes that regulate cardiac development may predispose individuals to CVM.

Additionally, human GATA-4 has been shown to regulate cardiac stress responses [49] [51], indicating that GATA-4 may have more than a developmental role in mammals.

Given that miRs regulate cardiac gene expression and are released in to the circulation in heart disease, it may be speculated that they can act as both mediators and diagnostic biomarkers in DHD.

These present studies also identify MuRF2 as the first ubiquitin ligase to regulate cardiac PPARα and PPARγ1 activities in vivo via post-translational modification without degradation and may represent a novel potential therapeutic target against heart failure in diabetes.

Montgomery, R. L. et al. Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility.

Sympathetic nerve input has been proposed to regulate cardiac growth and differentiation.

Given that these cardiac vagal neurons regulate cardiac parasympathetic efferent nerve activity, and given that the sympathetic and parasympathetic limbs dually regulate HRV, the decreased cardiac parasympathetic output may allow a greater influence of the sympathetic regulation of the heart.