Sentence examples for may regulate cancer from inspiring English sources
In addition, C1q interacts with a cellular membrane type-1 matrix metalloproteinase that may regulate cancer progression and metastasis [53].
Since expression of both CK2 and SIRT1 is upregulated with tumorigenesis and downregulated with senescence, the CK2-SIRT1 link sheds new light on how CK2 may regulate cancer development and aging.
It has also been suggested that the PGE2 produced through the COX-2-dependent pathway may regulate cancer–host communications that influence tumour progression.
The pathway and mechanism findings suggest prostasin may regulate cancer cell survival and/or chemoresistance by controlling CASPs/PAK2-p34 and thereafter signaling through apoptosis mechanisms.
Interestingly, CREB and miRNA-9 are involved in an auto-regulatory feedback loop since CREB itself can inhibit miRNA-9 expression, suggesting interplay between different types of non-coding RNAs may regulate cancer metastasis [ 112, 113].
Thus, we examined whether EBP2 may also regulate cancer cell proliferation.
Given the reported involvement of ezrin [ 34] and ankyrin [ 35] in cancer progression and of merlin in tumour suppression [ 17], we speculate that the spatial availability of CD44 to interact with specific cytosolic partners may differentially regulate cancer cell migration.
MMPs may also regulate cancer-related angiogenesis, both positively through their ability to mobilize or activate pro-angiogenic factors [ 35], and negatively via generation of angiogenesis inhibitors, such as angiostatin and endostatin, cleaved from large protein precursors [ 36].
In sum, all the genes in this module are associated with various cancers and cell death, so DAB2 may regulate ovarian cancer progression by mediating cell death signaling pathway, which may be a novel biomarker in clinical practice.
These results suggest that Th 2 type cytokines IL-4 and IL-13 locally-produced from TILs may regulate colon cancer adhesion by down-regulation of adhesion molecules.
PIPKIγ may regulate breast cancer progression via E-cadherin-β-catenin signal pathway.
