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Acute alternation of VEGF and Ang-1 in the ischemic core may mediate BBB leakage, whereas up-regulation of VEGF/VEGF receptors and Ang/Tie-2 at the boundary zone may regulate angiogenesis with neovascularization in ischemic brain.
Thus, Sprouty may regulate angiogenesis in normal and disease processes by modulating signaling by endothelial tyrosine kinases.
These findings suggested that Notch signaling may regulate angiogenesis of CNV by effecting on the activity of ECs.
Retinal microglia are directly involved in cytokine expression in response to ischaemia and may regulate angiogenesis in the neuropile [40], [45].
It is proposed that this protein may regulate angiogenesis and cancer progression.
15 This suggested that EIF2AK4 may regulate angiogenesis by modulating the immune system in PCH pathogenesis.
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The ability of TIMP-3 to inhibit VEGFR-2 mediated angiogenesis may play a critical role in the eye, regulating vascularization of the retina [ 24, 25].
The identification of neuropilins in endothelial cells suggested that class-3 semaphorins may also regulate angiogenesis.
LXRs may also regulate angiogenesis through modulation of cholesterol.
This protein may also regulate angiogenesis and cancer progression [ 27].
In addition to proteoglycan cleavage, members of this subgroup may also regulate angiogenesis.
More suggestions(15)
may regulate carbon
may repress angiogenesis
may inhibit angiogenesis
may influence angiogenesis
may regulate proliferation
may suppress angiogenesis
may regulate memory
may prevent angiogenesis
may regulate neurogenesis
may regulate inflammation
may regulate bone
may affect angiogenesis
may mediate angiogenesis
may regulate transcription
may regulate endocytosis
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