Sentence examples for may regulate alternative from inspiring English sources

MALAT1 may regulate alternative splicing.

We hypothesized that some risk SNPs may regulate alternative splicing.

Furthermore, H3K4me3 is enriched at alternative transcriptional start sites suggesting it may regulate alternative promoter use.

Since splicing factors may regulate alternative splicing of many different pre-mRNAs [ 17, 18], knocking out known splicing factors in mice generally has profound effects on embryo or young pup viability.

It has also been observed that antisense transcripts can drive alternative splicing and may even regulate alternative polyadenylation [ 46- 49].

In our study, mice were six-week old when high-fat diet feeding was initiated, whereas four-month old mice were utilized in the study carried out by Chen et al. The varied responses of SIRT1 LKO mice to a western-style diet at different ages raises the possibility that hepatic SIRT1 may selectively regulate alternative metabolic pathways at multiple stages of development.

Transcriptional targets for MYCN include splicing factors [ 29] which may in turn regulate alternative splicing of various target genes.

The preferential induction of splicing of BimS suggests that the mutant B-RAFV600E may regulate Bim alternative splicing in melanoma cells, and in particular, may suppress splicing to produce BimS.

Blocking one type of endocytosis may up-regulate alternative mechanisms, over-expression of mutant proteins may induce non-physiological cellular responses, and small GTPases may, via different sets of effectors, directly or indirectly control the activity of multiple endocytic pathways.

Alternatively, there may be other pathways (such as those that regulate alternative splicing) that function together with the sex-determination hierarchy to regulate reproductive behavior.

In summary, we have shown that TGF-β1 may alter the expression levels of the splicing factors that regulate alternative splicing of matrix proteins.