There are several arthritis models, each of which may reflect various variants of the heterogeneity of RA in humans.
There are several arthritis models, which each may reflect various variants of the heterogeneity of RA in humans.
Several Abi-1 or Abi-2 bands observed for the mouse brain lysates may reflect splicing variants, or the phosphorylation or partial degradation of these proteins.
The multiple clones of bacterial species that can be found in one individual may reflect neutral variants or may be the result of adaptation to the numerous ecological niches in the upper respiratory tract.
That is because unigenes may be split and re-merge until a unigene final form is attained; they may reflect splice variants [ 27, 28] and some of them may be incorrect [ 29].
Data suggest that patterns of inflammatory infiltrate are relatively stable over time and common to tissues from different joints from the same patient, including unaffected joints, suggesting that they may reflect true disease variants [ 6, 7].
Because none of these three SNPs maintained a statistically significant association with eGFR in multivariate models with simultaneous adjustment for the other two variants, we argue that these variants may reflect the presence of one common genetic source of phenotypic variation (Fig. 2).
Thus, global prioritization of EIF2 signaling components, in addition to enrichment within the down regulated transcript cohort of the PC variant, may reflect a cellular strategy of pre-emptive transcriptome recruitment to compensate for catastrophic system stress.
25 26 It is possible that the low OR (for CD susceptibility) and high prevalence of the ATG16L1 T300A variant may reflect the combined beneficial effects of protection from bacterial invasion and detrimental effects of susceptibility for intracellular microbial growth.
So while mtDNA variants stay mostly within the herd, Y-chromosomal variants may reflect the origin of sires as influenced by introgression and upgrading.
