The data presented in this study support, but do not prove, that p22 targets COPII vesicle trafficking; this is further complicated by the examination of cells by immunofluorescence primarily at 24 hpt, which may not reflect steady-state localization.
19, 45 Our data may reflect a steady-state distribution associated with the extended presence of patient antibodies.
Thus the doubled mammary tumor incidence in HFD-fed mice exposed to maternal TCDD here may reflect higher steady-state levels of both E2 and its toxic metabolites.
This suggests that other genes in this module also reflect steady state androgen levels, which may have important physiological and behavioural implications.
5. Product prices have sunk faster than the Titanic, but earnings reflect steady growth.
Our measurements reflect steady state H2O2 in the cells.
As siBRG1 cells are post-mitotic and senescent, the increased MITF occupancy may reflect a new steady state where MITF remains more stably bound to the NDRs established while BRG1 was still present compared to cycling cells where the NDRs are established and erased in a more dynamic manner.
This gap between sources and sinks of fixed N implies an oceanic nitrogen imbalance, which may reflect a non-steady-state of the oceanic fixed-N inventory, or result from over-estimation of loss processes and/or under-estimation of fixed nitrogen inputs [10], [13].
Thus, although transfer function phase or gain may reflect dynamic CA, both metrics could also partly reflect steady-state vascular properties such as compliance and resistance (Zhang et al. 2009).
Although one-time blood concentrations are thought to reflect steady-state levels in humans (Blount et al. 2011), they may be dominated by peak exposure events (e.g., showering/bathing, swimming) close in time to the blood draw.
