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Therefore, changes in levels of LC3 II and p62 proteins may reflect stages of the autophagy.
These differences may reflect stages in disease progression in individual animals, with the larger responses (also seen in the GK rat model [ 8]) representing an early stage of compensatory upregulation of responsiveness.
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Differences in cellular phenotypes produced by invertebrate and vertebrate ept/TSG101 alleles thus may reflect stage- or tissue-specific differences in the spectrum of proteins routed into the ESCRT pathway in each type of organism.
In pre-MBT embryos, the 46-kDa band in particular fluctuated, this may reflect stage-dependent changes in the protein or cell cycle-dependent changes as embryos synchronously divide.
This loss of stratification by PET nodal stage may reflect better staging and, therefore, more accurate treatment of nodal sites, although this is impossible to prove.
161 163 231–236 Several series have shown low morbidity and excellent medium-term survival after liver resection, with better outcomes than for patients whose tumours are not resected (although this may partly reflect stage of disease).
Speckled rattlesnakes from Ángel de la Guarda have proportionately small rattles [27], which may reflect initial stages of vestigilization of the rattling system in the absence of predators.
Up-regulation of hTERT and NOTCH1 in both tumorigenic OB3a and SS-OB2a NS/PCs suggests that a common mechanism may underly the malignant transformation of these cells, and that the histological differences between the OB3a-derived glioblastoma and the SS-OB2a-derived neuroesthesioblastoma may reflect different stages at which the NS/PCs have undergone neoplastic transformation in culture.
23 However, clinicians must be aware that abnormal concentrations of these markers may reflect advanced stages of PEI.
This cellular heterogeneity may reflect different stages of proliferation, differentiation and maturation; however, relatively little is known about these NP cell subpopulations.
The mechanism of Ig differential expression in M. bovis infected wild boar is unknown but may reflect different stages during mycobacterial infection.
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