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Microstructural abnormalities in white matter (WM) are often reported in Alzheimer's disease (AD) and may reflect primary or secondary circuitry degeneration (i.e., due to cortical atrophy).
These associations may reflect primary care residents' exposure to academia during residency training, which relies heavily on clinic precepting and use of community-based physicians [ 29].
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Although vaccination records were not available, the low responses observed in our study may reflect a primary immune response, as observed following a single dose of TT in adults with an unknown or distant history of TT vaccination [ 44].
Since the SNPs were related to height and the associations with BMC, BMD and bone area were attenuated adjusting for height, associations between variants in the region and measures of bone mass may reflect a primary influence on longitudinal growth.
Our findings for FM patients without previous use of CNS drugs may have reflected primary changes in rCBF in FM.
Weight seemed to lean strongly toward neuroimaging, which may reflect the authors' primary interests and expertise.
"It would be helpful to know how/why topic areas were chosen … may reflect the authors' primary interests" Doubtless the selection of articles reflects some influence of our own interests.
For lower penetrance disorders, inferences need to be more cautious and both depressive and substance use disorders fall into this category - i.e. cases known to secondary care may reflect more severe primary disorders, comorbidity, environmental disadvantage or referral biases.
There is also a pattern of prescribing drugs to most primary care patients which may reflect over-prescribing by primary care doctors.
The number of primary care physicians per capita may reflect improved access to primary care services and earlier access to prenatal services, which may reduce complications during pregnancy and, ultimately, the need for cesarean deliveries.
The emerging urban disadvantage may reflect the neglect of primary healthcare delivery in fast growing slums and informal settlements in urban areas.
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