Sentence examples for may reflect mutations from inspiring English sources

By correlating the residues in modeled proteins with positions with a significant difference in mean flexibility, we identified sites that may reflect mutations that enhance protein activity at low temperature.

The extent to which a change in Keq is determined by a change in ko vs. kc (given by the parameter Φ) may reflect mutation-induced changes in the transmission coefficient of the reaction [4], in which case Φ is a measure of the relative time within the reaction when the perturbed side chain flips from a C-like to an O-like conformation [5], [6].

These data indicate that the genetic heterogeneity observed in familial CCM may reflect mutation of different molecular members of a coordinated signalling complex.

We note that public heteroplasmic positions may reflect recurrent mutations as well as inherited hetreroplasmies [ 47].

Biologically, this makes sense because E2F3 acts downstream from both MYC and RAS, and therefore high E2F3 activity may reflect activating mutations in genes other than MYC and RAS.

Second, the elevated diversity observed in coding relative to non-coding regions may reflect different mutation rates or biases in the two types of sequence, which may in turn be related to the dramatically different base compositions [32] [34].

The accumulation of mutations in certain cancers may reflect a mutator phenotype with globally random mutations [4] [6].

A third possibility is that the mutations in patients 6 and 11 may reflect random somatic mutations independent of GC reactions.

Point mutation rates may reflect temporal variation in repair mechanisms.

Low αGL-A activity may not result from an inherited genetic mutation; it may reflect individual variation in its production or regulation.

The ancestral clones contained Pik3ca/Kdm6a mutations and may reflect the field-disease mutations shared among later tumors.