This may reflect the slightly modified pathology assessment criteria defined by this protocol.
In our view, participants' criticisms of the small group sessions may reflect a need to modify the session agendas and provide better guidance to participants about them.
That an intracellular parasite displays external antigens that are visible to the immune system is intriguing and may reflect the need to modify the environment in the highly differentiated human erythrocyte and the highly variable state of the circulation.
Considering that VCP governs protein degradation processes in both ER-associated ubiquitin-dependent protein degradation and autophagy [ 1, 4], the increase in cytoplasmic VCP in SALS may reflect a process that modifies these protein degradation systems.
Approximately 10%% of the samples analyzed in the setting shows moderately negative carbon isotope composition which may reflect normal marine signature slightly modified by variable contribution of CO2 derived from sedimentary organic matter decay (Table 2) (Bellanca et al. 2005).
However, five of the fadD genes (fadD21, 26, 28, 29, and 30) are those previously found to encode for fatty-acyl CoA ligases involved in complex lipid synthesis rather than lipid oxidation, which may reflect the need to maintain or modify the cell wall architecture in a challenging environment [42].
The absence of an effect of the high cholesterol diet on cholinergic responses in the ileum may reflect reduced concentrations of cholinergic modifying bile salts consequent to their enhanced absorption by the ileum relative to the jejunum [ 27].
This may reflect early changes in neurological gene expression modifying behaviour.
However, the penetrance of BRCA mutations is likely to be overestimated in published studies, as carriers are mostly ascertained based on the clustering of cancer in the family, which may reflect the presence of additional risk factors modifying the penetrance.
Proteoglycans (see 'Biological plausibility of the association of mammographic density and breast cancer risk' section above) bind growth factors, contribute to the mechanical integrity of tissues, may reflect the stiffness of breast tissue, and can modify tissue behavior [ 55].
