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Our data indicate that sepsis induces specific changes in monocyte TACE catalytic activity profiles that may reflect illness severity, whilst such changes were not seen in NI-SIRS.
Emphasis was placed on the lack of proof of causality between infection and outcome, and reactivation may reflect illness severity.
We hypothesized that monocyte TACE activity would be altered by sepsis and may reflect illness severity and/or cellular inflammatory balance.
Prematurity was associated with more frequent and longer duration of bronchiolitis episodes of care, which may reflect illness severity and/or perceived vulnerability.
We hypothesized that TACE activity profiles would be altered by severe sepsis and may reflect illness severity and/or cellular inflammatory balance.
This postulation that anxious preoccupation and helplessness-hopelessness may reflect illness representations rather than coping strategies is also supported by findings from the MAC [ 21] studies that indicate anxious preoccupation coping and anxiety are highly correlated.
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For this reason, data from young children, who presumably lack prior exposure and therefore immunity to influenza, may better reflect illness and viral shedding patterns of pandemic disease.
As both a very long and a very short PD may reflect inappropriate illness behaviour, future studies should examine the differences between these groups.
The somatic symptoms of depression (such as changes in weight) are unreliable as they may reflect the underlying illness [ 36].
Two out of four outliers with extremely high cortisol levels reported severe psychological problems during the last three months, which raises the question whether this new biomarker also may reflect severe psychological illness, although resent studies has shown decreased hair cortisol concentrations in patients diagnosed with generalized anxiety disorder [ 39].
The age distribution varied considerably by payer type, which may reflect the rising illness rates across age groups, the effect (for Medicaid in particular) of eligibility based on pregnancy, and the preponderance of people over age 65 in Medicare based on age-related eligibility.
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