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It may reflect disease severity and thus correlate with other disease severity biomarkers, but this correlation could be driven by any combination of differences in K i, V B and/or V A. The difference observed using normalised Patlak (( n{K}_i^{mathrm{Pat}} )) might be driven by the other quantities V B and/or V A to which it is sensitive.
Further, although normalisation of CA-125 values may reflect disease regression, this condition is not assured.
The association between resistin, ESR, and complement component 3 (C3) levels, observed in this study, may reflect disease activity [ 114].
Recent studies suggest that PR3-ANCAs reacting with the proform of PR3 may reflect disease activity better than those directed at mature PR3 [ 32].
Recently our studies found that reduced levels of erythrocyte CR1 may reflect disease activity in lupus patients by using specific monoclonal antibody CR1-2B11 [ 14, 15].
We have specifically compared the levels of key candidate proteins that may be relevant to pathogenesis or may reflect disease severity or activity.
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Decreased GMV of gyrus rectus may reflect disease-specific modifications of CM-MOH.
[10] [17] It has been suggested that AIDS is significantly associated with development of hepatotoxicity.[18] However, the reason for this association is currently unknown, but may reflect disease-induced alterations in bioactivation or detoxification of reactive metabolites, as well as immunedysregulation.
Those EMV-associated mi/mRNAs may reflect disease-specific causal mechanisms.
As denoted in our earlier study this may reflect disease-dependent changes in presystemic bioavailability or may simply reflect errors in parameter estimation using a population-based pharmacokinetic approach.
Overall, while the electrophysiological properties of pilocarpine-treated GCs share common hyper-excitable characteristics with GCs from the α-CaMKII hKO mice, the mechanisms by which iDG was achieved in the two mouse models may reflect disease-specific differences in neural circuitry and the manner in which the DG relays and processes afferent and efferent connections within the hippocampus.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com