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Alternatively, some of these parallel changes, and reversals may reflect constrains upon the sequences, where two alternative amino acids may be tolerated at these locations.
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The difference between both analysis may reflect differences in selective constrains through the action of purifying selection being higher in the upstream part of the pathway rather than differences in the selective pressures by means of positive selection.
In contrast to the increased mobility observed after IR or enzymatically induced DSBs, spontaneous Rad52 foci are constrained, which may reflect recombination between sister chromatids in the context of DNA replication (Dion et al. 2013).
Again this observation may reflect a higher degree of sequence constrains in target site selection for piggyBac than for Tol2.
However, it remains unclear whether these differences may reflect a constitutively impaired response to biomechanical constrains or may reflect changes in ECM structure and biomechanical properties, consequently modifying mechanical signal transduction and leading to a slightly different outcome.
As in other C4 species, leaf yellowing observed in the drought treatment may reflect N retranslocation out of the leaves [ 57], which may constrain physiological recovery from drought.
That the SNP rate obtained by Geraldes et al. is substantially lower than our own may reflect that fact that they studied only expressed sequences, which are more likely to be constrained by natural selection.
This observation may reflect natural selection for survival and fitness in the wild and suggests that the release of selective constrains in genes related to disease resistance in domestic breeds could have lead to a faster accumulation of genetic diversity among these genes.
The positive correlation may reflect that living conditions in many US states limit access to education (both formal and informal) and constrain engagement in further learning for pleasure.
This may reflect the current culture of medical training: in one prior study, 80% of surgical residents reported feeling constrained by time when caring for terminally ill patients and their families [ 16].
This may reflect their embarrassment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com