This may reflect aggregation of tau monomers into aggregates of varying number, size, and single channel conductance.
Contrast agents are not inherently quantitative, and spots on images may reflect islet aggregates rather than single islets.
The differences between the two types of aggregate, in particular the number of aggrecan molecules per aggregate, may reflect differences in their assembly, stability, and turnover, which therefore give them different mechanical and biological properties [ 54].
The physical basis for the increase in infectious titre seen after exposure to pronase E remains unexplained, but may reflect changes in PrP aggregate size with concomitant alteration of specific prion infectivity [8] or increased bioavailability of prions following removal of other proteins.
Activity of IB aggregated enzymes may reflect the presence of a percentage of properly folded functional protein [ 14].
The ability of OPA1 to aggregate liposomes may reflect its ability to form intermolecular complexes in trans, a property that has been proposed to be important for its biological activity (5, 6).
The iron starved wild type cells also showed a decreased F720 (F717)/F685 ratio, which may reflect the presence of PSI-less IsiA aggregates [31] since the IsiA-PSI supercomplexes have a very small 685 nm emission [28], [31].
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According to recently reported immune EM studies, in skin laminin and collagen IV network were more intensely linked by perlecan aggregates than by nidogens which may reflect a progressed state of BM maturation [ 84].
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