Sentence examples for may reduce uptake from inspiring English sources

Inclusion of a PEGylating lipid can enhance LNP colloidal stability in vitro and circulation time in vivo but may reduce uptake and inhibit endosomal release at the cellular level.

Thus, the use of non-residualizing labels may, in principle, reduce uptake of affibody-delivered radioactivity in excretory organs without compromising uptake in tumors.

The presence of L-glutamine in the culture medium may reduce FLT uptake, as glutamine is a source of thymidine monophosphate competing with FLT uptake through the de novo pathway.

Increased activity of NHE1 will also decrease extracellular pH (pHe), an effect that may reduce cell uptake of certain chemotherapeutic agents [ 21].

Hence, down-regulation of porin expression may reduce colistin uptake by the A. baumannii 53264 strain and explain its resistance toward colistin.

Interestingly, CAF diminished the insulin-stimulated serine phosphorylation of Akt (Ser473) and GSK3β (Ser9), which may reduce glucose uptake in response to insulin and lipid accumulation.

Drugs that interfere with the reuptake of bile acids may reduce the uptake of fat-soluble vitamins such as vitamin E [ 44].

Ethanolamine released from cells may reduce Cho uptake, regulating the membrane PtdEtn:PtdCho ratio and influencing the action of PtdEtn-binding proteins such as RKIP and the anti-apoptotic hPEBP4.

In the case of treatments based on cationic antineoplastic drugs, the combined treatment may reduce the uptake of these drugs by the tumor and hence decrease the efficacy of the chemotherapy [ 43 ].

Though mice are commonly used as model animals for preclinical evaluation of SL vaccines, these rodents have a keratinized SL mucosa that may reduce the uptake of antigen via this route.

The effect of radiation and chemotherapy can be significantly affected by the tumor microenvironment, thus tumors with extensive hypoxia are more resistant to radiation and some forms of chemotherapy, and poor blood perfusion may reduce the uptake of chemotherapeutic drugs [ 10].