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Involving larger populations of neurons in motor planning and execution may reduce neuronal noise and lead to less variable performance.
Propranolol, on the other hand, may reduce neuronal excitability and susceptibility to CSD via a beta-adrenergic blockage.
In addition, due to the coupling of TRESK to the histamine H1 receptor, the channel may reduce neuronal excitability in inflammatory conditions when histamine or other inflammatory modulators are released into the surrounding tissue.
In summary, DHA may reduce neuronal activity through hyperpolarization of the cell membrane and by reducing the firing activity in NonTg mice.
We speculated that increases in astroglial GSH may reduce neuronal ROS production in our cultured system, as reported by García-Nogales et al. (2003).
In conclusion, we describe an unexpected role for glucose in cellular protection, and strategies to supplement neuronal glucose levels may reduce neuronal proteotoxicity.
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For implanted devices with large feature sizes, steric blockade of both membrane bound signaling molecules and soluble signals, including growth factors, may reduce neural survival signaling by decreasing neuronal input signals and ultimately leading to apoptosis.
31, 32 Thus, we hypothesized that drugs that upregulate this pathway may potentially reduce neuronal stress in this model system.
Previous work has established a role for hypothalamic pro-opiomelanocortin (POMC) neurones in reducing feeding due to satiety, suggesting that signals promoting feeding may reduce POMC neuronal activity.
Supplementation with ω-3 increases serotonin levels in the brain of stressed rats [ 60], which in turn may reduce BNST neuronal excitability by activation of the 5-HT1A and 5-HT1B.
Therefore, vitamin E supplementation may have minimized these events to reduce neuronal death in group DE2.
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