The longer duration of dual antiplatelet therapy required with DES [32] may reduce long-term adverse event rates independently of stent selection [33].
In particular, NRTI-sparing regimens may reduce long-term toxicities.
Thus initiation of treatment in childhood is important for most patients and may reduce long-term sequelae.
In type 2 diabetes, there is evidence that more-intensive treatment of glycemia in newly diagnosed patients may reduce long-term CVD rates.
Multidisciplinary ICU follow-up may reduce long-term symptoms of posttraumatic stress and post-ICU depression for women after critical illness.
Addressing the health needs of migrants improves migrant health, avoids stigmatization and marginalization, may reduce long-term health and social costs, protects global public health, facilitates integration, and contributes to social and economic cohesion and development.
Effectiveness of various treatment modalities has been summarized by others who conclude that radiation, chemotherapy and hormonal therapy may reduce long-term mortality by up to 57% [ 66, 103– 105].
Our choice of specific antihyperglycemic agents is predicated on their effectiveness in lowering glucose, extraglycemic effects that may reduce long-term complications, safety profiles, tolerability, ease of use, and expense.
Nor can they address the possibility of adverse consequences to the extent that extrinsic incentives may reduce long-term intrinsic motivation to engage in safe behaviours after incentives are withdrawn.
In addition, there is evidence that avoiding wide-field radiotherapy throughout CRT may significantly reduce long-term toxicity (Jenkins et al, 1995).
