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Sequence variants may reduce expression of GC or ability of vitamin D binding protein to bind to 25(OH D.
In order to test the hypothesis that chromatin deacetylation sites may reduce expression correlations among neighboring genes, we again performed a hypergeometric test.
Thus, it appears that the additional sequences introduced by the loxP site in the original Clontech Creator system vectors may reduce expression levels.
These observed differences in apoptosis may be owing to alterations in the MMR system (e.g., MSH2 (Krynetskaia et al, 2003)) Sensitive cell lines may have higher expression of these proteins or may induce expression after treatment more efficiently; they may be absent in resistant cell lines or may reduce expression after treatment.
The rationale for testing a dopamine 3 agonist in fibromyalgia is based on evidence that excessive adrenergic arousal may fragment sleep, and enhancement of dopaminergic neurotransmission at the D3 receptors in the mesoliombic hippocampus may reduce expression of arousal and improve sleep.
The miRNAs with the largest effect in our study, miR-10b-5p, putargetsy targets HTT by binding to two 3′UTR sites (both 7mer-1A seed, positions 2742 2748 and 3301 3307) and may reduce expression of HTT although it is not clear whether or not this would be neuroprotective [ 33].
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The study also confirms the observation that removal of protein components of snoRNPs may strongly reduce expression of the corresponding class of snoRNAs also applies in C. elegans, and that this reduction in expression is experienced across entire sets of related transcripts.
Tax expression may reduce the expression of Foxp3, which regulates Treg development and function [15].
One possible treatment for Huntington's disease may be to reduce expression of mutant Huntingtin in the brain via RNA interference.
In consistent with this relationship between SOD2 and Sirt3, our results showed that the expression of SOD2 was also correlated with that of Sirt3 in 15 HCC specimens, which supported that Sirt3 may reduce the expression level of ROS via the activation of SOD2.
Our results indicated the possibility that BTX-A may reduce the expression of the TRPV1 receptor in neurons of the TG innervating the dura mater, which may account for its alleviating action against headache disorders.
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may upregulate expression
may have expression
may modulate expression
may exhibit expression
may prevent expression
may reduce return
may reduce demand
may affect expression
may induce expression
may regain expression
may reduce liquidity
may promote expression
may reduce inflammation
may show expression
may find expression
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