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It also may reduce "circulating concentrations of insulin and related growth factors," the guidelines state.
Thus, SNPs within GC may reduce circulating 25(OH D levels.
First, physical activity may reduce circulating levels of insulin, hormones, and other growth factors (McKeown-Eyssen, 1994; Giovannucci et al, 1995).
Further study is required to clarify the temporal relationship between hysterectomy and alteration in serum VEGF levels and to elucidate the precise mechanisms by which the postmenopausal uterus may reduce circulating VEGF.
Thus, corresponding to the AICR/WCRF criteria presented earlier (1) it is well established that physical activity helps to prevent weight gain, improves insulin sensitivity and may reduce circulating oestrogen levels; these biological factors are relevant to endometrial cancer risk.
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It remains to be determined if IL-17 antagonists may directly reduce circulating and synovial B-cells in a similar way to current anti-TNF biologics or anti-B cell therapies [39], [40].
Non-DL-PCBs do not cause AhR-dependent effects but induce microsomal cytochrome P450 enzymes 2B and 3A that may also reduce circulating T4 levels (Khan et al. 2002).
This action is sufficient to reduce circulating levels of thyroid hormone and may induce neurotoxicity in developing organisms (U.S. EPA 2002; York et al. 2005a).
This may derive the efficacy of B. ceiba's to reduce circulating lipids, free fatty acids and thereby prevent fatty liver [ 41].
Intuitively, optimising somatostatin analogue therapy should reduce circulating vasoactive substances and carcinoid syndrome and therefore may stabilise CHD.
These findings may have the potential to affect weight reduction in humans and subsequently reduce circulating AGE levels.
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