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These changes may reduce bacterial virulence.
Specific probiotics have anti-inflammatory effects and may reduce bacterial translocation.
Continuous irrigation of the wound area may reduce bacterial load and in theory decrease the risk of infection.
Others have suggested that nitric oxide substrates may reduce bacterial translocation by preserving microvascular blood flow [ 10].
Results indicate that vaccination may reduce bacterial load in the environment and human exposure to C. burnetii.
This suggests that some antibiotics such as carbapenems with activity against ESBL-E may reduce bacterial load of the organism as has been reported previously for VRE [ 23].
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In addition, glutamine supplementation may also reduce bacterial translocation [ 10].
8 Thus, the CD-associated variant in ATG16L1 may both reduce bacterial invasion and reduce clearance of microbes that successfully invade the cell.
One possible explanation for this result is that loss of a particular exoenzyme may reduce the bacterial invasive ability, permitting the host to mount a better defense.
Sutures can be coated with antibacterial substances that may reduce the bacterial load in the wound.
Studies with infected mice immunized against S. aureus coagulases important for abscess formation and bloodstream infection suggest such an approach may be used to reduce bacterial load and protect against severe disease in humans.
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