It was previously demonstrated that meningococcal serogroup C conjugate vaccines reduce asymptomatic carriage [ 17], therefore a vaccine that protects a high percentage of adolescents may lead to lower incidence of IMD in other age-groups.
We found evidence that introducing screening-preventative strategies for asymptomatic pregnancies may reduce the rate of PTD.
Examining this in an asymptomatic population may reduce the potential for any associations identified being due to reverse causation.
While treatment of asymptomatic AVF in pregnancy is not standard of care, two promising trials in the UK have shown that treatment of asymptomatic AVF may reduce preterm birth rates by up to 60%%.
Emerging research suggests that treatment of asymptomatic hyperuricemia may reduce the risk of some adverse health outcomes, such as mortality and cardiovascular disease; [ 23- 27] therefore, treatment of asymptomatic hyperuricemia is currently being discussed to prevent adverse health outcomes [ 28, 29].
We hypothesised that earlier diagnosis of a tumour or its precursor lesion (ESD) by screening of asymptomatic high-risk individuals may reduce mortality and the individual and societal burden of this fatal cancer (Lao-Sirieix and Fitzgerald, 2012).
Although these data suggest that searching for and eradicating H pylori may reduce the incidence of gastric cancer in healthy asymptomatic infected individuals, the 95% confidence intervals are wide and the result is heavily dependent on one study.
23 Even though there is no clear evidence of the advantages from screening or treatment of all women who have asymptomatic BV, evidence suggests that screening and treatment in pregnant women may reduce PTB and low birthweight infants.
Treatment of asymptomatic bactiuria is considered standard of care in high-income settings, and may reduce low birth weight and maternal pyelonephritis.
This screening approach could help identify asymptomatic cases and correctly identify symptomatic cases; combined with the correct treatment regimen, this screening may reduce pregnancy complications and HIV genital viral load in HIV-positive women.
