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Alternatively, histone-modifying enzymes may recognize similar or different sequence signals among chromosomal domains.
The conservation of the signatures, especially the Q-type implies that ZF types with the same signature may recognize similar DNA sites.
OR genes of different species in the same cluster may recognize similar odorant substances because it has been reported that ORs sharing more than 60% in their sequence homology bind to odorants with similar chemical structures [ 20, 21].
The homology between the three S. cerevisiae Mig transcription factors and the two putative Mig-like transcription factors found in Z. bailii CLIB213T or in the ISA1307 strain was limited to the DNA-binding domain, suggesting that all these transcription factors may recognize similar DNA-binding sites, as found in other fungi.
Have the authors any further information from DNase footprinting, gel shifts with point mutations in the Pol III promoter elements etc. on this point, especially in relation to their suggestion in the Discussion that " MAF1 and Pol III/TFIIIB may recognize similar DNA elements"?
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Based on sequence similarity, we identified 195 clusters, where elements of one cluster may possibly recognize similar substrates.
Second, there is a vast literature concerning 'crossreactive' antibodies that may recognize very similar epitopes from unrelated targets [26], [27] or from closely related proteins, e.g. TB10.3 and TB12.9 in the case of peptides derived from TB10.4 [28].
This amino acid contributes to the determination of sequence specificity by the homeodomain, suggesting that these proteins may recognize very similar DNA sequences [ 23].
If these two TFs recognize similar DNA binding site motifs then it is possible that these genes may interfere with each other's activity or they may potentially serve compensatory roles[22].
They may recognize CCTTC or similar target site with 1-bp difference.
Molecular modeling suggests that the bLysG domain may recognize glycan in a similar manner to MltE.
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