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Activating interventions may rather exert beneficial effects through an implicit change of adverse cognitions like fear-avoidance beliefs [ 23, 24].
Furthermore, unlike RIG-I and MDA5, the DDX3X function in the IRF pathway does not rely on its ATPase activity, implying that it may rather exert an effect as a scaffold than as a helicase.
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Considering the apparent lack of a gross difference in the formation of nuclear inclusions by Ataxin-3 cleavage in fly neurons, it is possible that ∼37 kDa cleavage products may not be readily recruited into macroscopic inclusions, but rather may exert toxic effects as soluble monomers.
On the other hand, the p.R407C mutation is compatible with secretion, but rather may exert its pathogenic effect by disrupting interactions with ADAM proteins.
It may, rather, be something more systemic.
The authors considered this to indicate the fact that ADM in combination with 4OHT may exert a rather negative anti-tumour effect.
These findings are extended by the observation of association with UC overall but not with any known UC subphenotype group, suggesting that IL23R variants may exert a rather generic effect on chronic intestinal inflammation, although the effect size in UC does appear to be smaller than in CD.
Disease control may be particularly important when evaluating new molecularly targeted agents that may exert greater cytostatic rather than cytotoxic effects.
Board members may depart or may attempt to exert their authority -- often by replacing the artistic director.
Because a lower risk for diabetes has especially been observed in the moderate range of alcohol intake [ 46], a high wine intake at the population level may exert a detrimental rather than a beneficial effect on risk.
They suggested that low levels of CAS may exert a stimulatory, rather than suppressive, effect on the cochlear enhancer; this hypothesis is supported by an increase in the suppressive effect observed at higher levels of CAS.
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CEO of Professional Science Editing for Scientists @ prosciediting.com