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From a practical point of view, the occurrence of nonsynchronous and chaotic motion in rotating machinery is undesirable and should be avoided as they introduce cyclic stresses in the rotor, which in turn may rapidly induce fatigue failure.
Recent work has shown that stress rapidly increases the level of circulating stress-hormones and that in hippocampus (HPC) corticosterone (CORT) binds to membrane mineralocorticoid receptors (MR), which may rapidly induce the release of glutamate through non-transcriptional mechanisms [11], [12].
This cooperation may rapidly induce extensive production of M1 cytokines that orchestrate a complex response to these various situations.
For instance, CTL may kill through Fas pathway (Ostergaard et al, 1987; Rouvier et al, 1993), and granzymes entering target cells (Froelich et al, 1996; Jans et al, 1998; Pinkoski et al, 1998; Edwards et al, 1999) may rapidly induce their DNA fragmentation-based apoptosis (Heusel et al, 1994; Shresta et al, 1995).
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The DNA damage caused by albicidin may rapidly have induced the mutation of DNA gyrase A gene and thus stopped the process of genome erosion, possibly explaining the distinctive genomic characteristics of X. albilineans.
While these may be rapidly induced within 2-3 years following hrHPV infection, progression to invasive cervical carcinoma may still take another 10-30 years [ 5, 11, 12].
The successful spread of this species to higher altitudes and latitudes may be explained by its ability to rapidly induce a heritable low-temperature phenotype (cold hardiness in eggs).
HDACi are reported to rapidly induce cell cycle arrest and induce tumor cell-selective apoptosis.
Selection on this pathway in wMel may indicate a mechanism for rapidly inducing widespread transcriptional changes in response to shifting habitats.
Because individuals of these two species had the same thermal history, this variation between species is not likely due to differential heat-hardening but, rather, may represent either higher constitutive, or more rapidly induced, Hsp expression in Diplosoma.
Naturally acquired sexual stage-specific antibody responses may be acquired after exposure to gametocytes [12] and rapidly induced as part of the initial response to infection [19], [20].
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