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Identification of such candidate genes may lead to a better understanding of the pathogenesis of S. suis and may provide substrate for the discovery of new vaccines.
The RBR ligase Parkin has been found to associate with SCF-type ubiquitin ligases, raising the possibility that adapter proteins may provide substrate specificity for a subset of these E3s [ 43].
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Release of membrane lipids follows immune cell activation [34], and may provide substrates used by Candida for RvE1 biosynthesis; alternatively dietary sources of EPA and DHA may also serve as substrates for resolvin biosynthesis.
The patchy nature of cardiac iron deposition may provide substrates for reentry and risk of fatal arrhythmias in patients with beta-thalassemia, which explains the appearance of premature ventricular contractions, ventricular tachycardia, and late ventricular potentials [ 88, 89].
In kairomone exposed D. magna, phosphomannomutase may therefore provide substrates important for signalling pathways involved in the formation of inducible defences.
Studies have demonstrated persistent hyperexcitability of dorsal horn neurons which may provide a substrate for CNP.
Our longitudinal findings may challenge the view of recovery as ending within the first year following onset, suggesting that the RH may provide the substrate for ongoing plasticity in the damaged brain.
This co-ordinated slow wave oscillation may provide a substrate favoring hippocampal-neocortical dialogue for off-line memory consolidation [8].
Although restitution heterogeneity has been described in the normal heart [27], increased heterogeneity may provide a substrate for arrhythmia in diseased hearts [29].
In addition, the presence of a low copy-number yet dominant population of potential pathogens may provide a substrate for full blown bacterial infection following otherwise self-limiting viral infections [22] as well as following pandemic influenza [10], [11].
Alternatively, DE may provide a substrate for NOS uncoupling that is not related to ROS.
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CEO of Professional Science Editing for Scientists @ prosciediting.com