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Given this previously undescribed role in enhancement of virion maturation, the precise consequences of CIITA expression during the HIV replicative cycle may provide rationale for the development of novel antiviral therapeutics.
The data may provide rationale for prospective cohort studies to establish whether HDL apoC-III and associated change in HDL function predict DM2 and whether lifestyle and pharmacological interventions can improve the abnormalities leading to diabetes prevention in youth and reduction in the increased female prevalence.
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Consistency may provide a rationale for a limited exercise of analogy.
This may provide a rationale for the therapeutic use of long-acting somatostatin analogues for treatment of this disease.
It is conceived that cocktails of defined epitopes or chimeric protein arrangements, including the target epitopes, may provide a rationale design capable to elicit convenient humoral or cellular immune responses.
Together, these findings may provide a rationale for initiating treatment with combined quetiapine XR and lithium in patients with severe acute manic symptoms, rather than escalating the dose of monotherapy up to the highest dose approved, and hence also for subsequent use of this combination as maintenance treatment to prevent recurrence.
This work demonstrates a new way to significantly decrease the density of a thermoset polymer without compromising desirable properties such as high Tg and low coefficient of thermal expansion, and therefore may provide sounder rationale for molecular-based design of epoxy-based coatings.
While the imbalance in conventional forces may provide a rationale for the continued deployment of tactical nuclear weapons (following the logic of the Cold War deployments), NATO would be highly unlikely to threaten escalation in the event of strictly conventional attack even in the absence of an explicit "No First-Use" policy.
More specifically, they may provide a rationale for the consistent epidemiologic and neuropathologic association of AD with homocysteine elevation and folate deficiencies [15], [16], since folate ultimately provides the methyl group for DNA methylation.
Since a similar preference for GPO-containing sequences has also been found for LAIR-2, this may provide a rationale for the inhibitory effect of LAIR-2/Fc on GpVI-collagen interactions.
It may provide a rationale for the development of novel Hsp90-based therapeutic strategies [ 5].
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CEO of Professional Science Editing for Scientists @ prosciediting.com