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We contend that coevolution of Nrf2-activating secondary metabolites by fungi and other extant microbiota may provide prospective compound leads for the design of new therapeutics to target activation of the human Keap1 Nrf2 pathway for treating degenerative diseases of ageing.
29 If this model is followed, process data may provide prospective insights into why evaluators might subsequently expect to see positive or negative overall effects and generate hypotheses about how variability in outcomes may emerge.
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In addition, accumulating studies have recently shown that herbal preparations may provide a prospective alternative in the treatment of dementia for their better compliance and lower side effects.
Although few anti-microtubule cancer drugs have produced a positive effect on EHCC in current clinical practice, the combination of taxane and anti-STMN1 drugs may provide a prospective therapy against various cancers in the future.
Further studies revealing the immanent connection of FGF21 with the pathology of diabetic peripheral vascular disorders may provide a new prospective strategy for LEAD.
The data may provide rationale for prospective cohort studies to establish whether HDL apoC-III and associated change in HDL function predict DM2 and whether lifestyle and pharmacological interventions can improve the abnormalities leading to diabetes prevention in youth and reduction in the increased female prevalence.
The AMPK-mediated PLD1 pathway may provide attractive target molecules for prospective pharmacological studies or genetic manipulation.
Prospective studies may provide definite evidence.
In the same vein, the promising characteristics of Cygb may provide the basis for a prospective role in clinical treatments.
Further prospective studies may provide more evidence to determine the additional role of irinotecan in the treatment of recurrent malignant glioma.
However, this observational prospective study may provide a representative image of the real-life scenario in the use of CF sensing for AF ablation.
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