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Our work provides comprehensive understanding of lipid accumulation and new insights which may prove promising for the effective lipid enhancement and particularly DHA production in C. cohnii.
Although experimental validation is required to determine the suitability of such an approach for the discovery of novel drug targets, our computational evaluation shows that, at least for some protein families, our approach is highly successful (up to ROCAUC), and therefore may prove promising for integrative approaches toward computational drug repurposing.
In the final section, we highlight current experimental therapies that may prove promising in preventing and treating post-traumatic epilepsy.
The design of this single-dose combination therapy with PC-SA-SSG for VL, having reduced toxicity and long-term efficacy, irrespective of SSG-sensitivity may prove promising, not only to overcome SSG-resistance in Leishmania, but also for drugs with similar resistance-related problems in other diseases.
For example, external-beam and partial liver irradiation may prove promising in this difficult multidisciplinary approach, as the dose of radiation can be adjusted and precisely targeted to parts of the liver [ 55, 58].
Another line of investigation that may prove promising is to examine the evolutionary lability vs. conservatism of pollinator associations in relation to attraction traits (rewards, advertisements) and traits affecting floral pollinator fit and pollen/stigma contact points.
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Other approaches may also prove promising.
The solvent extracts of the test plants exhibited a range of antibacterial activity and may therefore prove promising in relation to the development of new antibiotics.
In addition, although targeting individual members of the antiapoptotic Bcl-2 subfamily may initially prove promising, recent studies with ABT-737 suggest that resistance to the compound is a consequence of the ability of cancer cells to adapt and express other Bcl-2 subfamily members.
With adhesives for biomedical use, studying sticky materials found in nature may prove particularly promising.
But the company now reckons that shale gas, which it thinks can be found at greater depths than the coal in the area, may prove more promising.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com