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Taken together these experiments demonstrate that global DNA hypomethylation induced by 5-aza-2-deoxycytidine may promote specific aspects of tumorigenesis in rat chondrosarcoma cells.
Within fertility research, acupuncture demonstrates beneficial hormonal responses with decreased miscarriage rates, raising the possibility acupuncture may promote specific beneficial effects in early pregnancy.
This raised the possibility that TOUSLED may promote specific cell divisions within the meristem, rather than having a general proliferative effect [ 43].
Collectively, our findings indicate that canonical Notch signalling is lost in urothelial carcinoma mainly via inactivation of NOTCH1, which in normal urothelium may promote specific steps of urothelial differentiation.
Rather, financial losses may promote specific instances of learning that Redish calls "state splitting," 77 and that gambling researchers recognize as "hindsight bias," the explaining away of losses in a manner that does not erode the player's belief in his/her ability to win.
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Thus, besides the effect of muscle fat accumulation on insulin sensitivity, muscle lipid accumulation may also promote specific changes in muscle protein metabolism.
The surface of the nanocarriers can also be modified with ligands that may prolong blood circulation and promote specific types of endocytosis and cellular uptake into tumor tissue.
Direct application of iCM reprogramming in vivo may promote patient-specific precision therapy by reducing the accompanying costs and efforts, which are considerable with in vitro generation of patient-specific iPSC-CMs.
Here, serial ganciclovir treatments and slow toxin clearance may promote non-specific bystander killing due to inherent vascular defects that resemble those found in neoplastic tumours, the most intensely studied tissue model for bystander killing.
We hypothesize that low temperatures may promote non-specific binding of transcriptional or initiation factors to incorrect sites and thus confer a selectional advantage to a greater abundance of OSCs.
Our findings may not be detailed enough to promote specific prevention programs, but they clearly demonstrate the need for such initiatives.
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